New biological identity of inhaled nanoparticles revealed

said braka 12:12 AM
The Nanotechnology Consumer Products Inventory

maintained by the Woodrow Wilson International Center for Scholars has listed 1,814 nano-enabled consumer products, many of which have a potential safety hazard if inhaled. However, their potential biological risks are still largely unknown.
University of Hawai'i at Mānoa College of Engineering Professor Yi Zuo has developed a new method to reveal the  of nano-bio interactions in the lungs. This research was published in the July 2017 issue of the scientific journal ACS Nano, "Unveiling the molecular structure of pulmonary surfactant corona on nanoparticles."
Zuo's study showed that once the inhaled nanoparticles enter the lungs, they are quickly wrapped with a biomolecular corona made of the natural pulmonary surfactant. The entire surface of the lungs is lined with a lipid-protein pulmonary surfactant film, which serves an important physiological function of host defense and surface tension reduction. The pulmonary surfactant corona provides the inhaled nanoparticles with a new identity in their subsequent interactions with the biological system, such as their clearance and cellular toxicity.


Read more at: https://phys.org/news/2017-08-biological-identity-inhaled-nanoparticles-revealed.html#jCp